The updated edition of the third of three vollumes on Medical Physics presents modern physical methods for medical therapy with a focus on tumor treatment. It provides background information on radiation biology, radiation response of tissues, and linear energy transfer through radiation. Therapies with external radiation sources (x-rays, protons, neutrons) as well as internal radiation sources (brachytherapy) are discussed in detail. Other chapters deal with the use of lasers and nanoparticles in modern medicine. This volume closes with a short chapter on medical statistics. NEW: highlighted boxes emphasize specifi c topics; math boxes explain more advanced mathematical issues; each chapter concludes with a summary of the key concepts, questions, exercises, and a self-assessment of the acquired competence. The appendix provides answers to questions and solutions to exercises.

Hartmut Zabel received his doctorate in 1978 from the LM University of Munich in the field of physics on a topic in condensed matter physics. He then spent a year as a postdoctoral fellow at the University of Houston, Texas, and joined the faculty of the University of Illinois at Urbana-Champaign in 1979 as Assistant Professor, where he was promoted to Associate Professor in 1983 and Full Professor of Physics in 1986. In 1989 he received a call to the Ruhr University Bochum and held the chair for experimental physics/condensed matter physics from 1989 to 2012. He maintained his connection to the University of Illinois as Adjunct Professor of Physics. After his retirement in 2012, he was first a Senior Professor at the Ruhr University and from 2014 to 2018 Distinguished Guest Professor at the Johann Gutenberg University in Mainz. In addition, he was a guest researcher at various universities and institutions, i.a. at Brookhaven National Laboratory (USA), Risø National Laboratory (Denmark), University of Kyoto, National Institute of Science and Technology, Gaithersburg-Washington, KTH Stockholm, and Uppsala University (Sweden). He was also member and chairperson of various scientific committees and advisory bodies, including those at the Paul Scherrer Institute in Switzerland, the Institut Laue-Langevin (Grenoble, France), Argonne National Laboratory, and the Helmholtz Center Berlin. In 1996 he was elected a Fellow of the American Physical Society, in 2001 he received an honorary doctorate from the KTH in Stockholm, In addition to his scientific work at the University of Illinois and the Ruhr University Bochum with over 500 publications in peer-reviewed scientific journals on the structure, dynamics, magnetism and superconductivity of solids, he was supervisor and co-supervisor of more than 50 doctoral students in Urbana, Bochum and Mainz, organizer and co -organizer of numerous international workshops and conferences, editor and co-editor of five books, and guest lecturer at many summer schools in Europe. i.a. he was a guest lecturer in the European Graduate School "HERCULES" in Grenoble for the last 30 years, lecturing on the topic of scattering experiments with synchrotron radiation and neutrons. At the beginning of 2000, the medical department at the Ruhr University Bochum developed a new study concept based on the model of the University Hospital Charité in Berlin: problem-oriented learning (POL). As a representative of the physics department, Hartmut Zabel was involved in the curriculum development. In addition to the standard physics course for medical students, he also supervised the physics-related seminars in the POL teaching format. Finally, he developed a new lecture series on "Medical Physics" for physics students and initiated a master course "Medical Physics" at the Ruhr University Bochum, which was later established and certified.