The novel carriers have been exploited through almost all the routes of administration. Many newer carriers are evolving with the advent of technology and the demand of targeted delivery like microemulsions. Microemulsions are clear, stable, isotropic mixtures of oil, water and surfactant. These systems are currently of interest because of their considerable potential to act as drug delivery vehicles by incorporating a wide range of drug molecules. In addition to oral and intravenous delivery, they are amenable for sustained and targeted delivery through nasal, pulmonary, vaginal and topical routes. Intranasal drug delivery system is a promising alternative route of administration for poor bioavailability drugs and it has advantages in term of increase patient acceptibility and compliance.The intent of the paper focuses on use of microemulsion technology in intranasal drug delivery along with mechanism.

Mrs. Kumkum Sarangdevot, is presently working as Asst. Professor o Pharmaceutics, at Pacific college of Pharmacy, Udaipur. She completed her graduation and M. Pharm. from B. N. college of Pharmacy, Udaipur and pursuing her doctorate from Pacific University, Udaipur. She has published several artical and research papers in many journals.