In contrast to the limited distribution of Phyllomedusa nordestina to the region known as caatinga, P. hypochondrialis is found spread over biogeographically different habitats, including the rich Amazon rainforest biome. We propose to summarize all main findings for the frog P. nordestina, endemic to the Brazilian Northeastern and included within the clade of P. hypochondrialis, making a comparison between the peptidoma and transcriptoma analysis, seeking to contribute to solidify the potential future use of this frog skin active peptides for biotechnological or therapeutic applications.

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BoD - Books on Demand
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Dr Mirian Hayashi has at least 5 new patent applications, which protect the use of toxin peptides and analogues for pharmaceutical purposes, and more than 40 publications including 3 reviews and 6 chapters of book, describing the identification and characterization of novel toxins, and subsequent study of their mechanism of action.