Over the past twenty years, thousands of physicians have come to depend on YamadasTextbook of Gastroenterology. Its encyclopaedic discussion of the basic science underlying gastrointestinal and liver diseases as well as the many diagnostic and therapeutic modalities available to the patients who suffer from them wasand still isbeyond compare. This new textbook,Principles of Clinical Gastroenterology, is designed to inform practitioners on the features of the major clinical disorders in gastroenterology and hepatology from the point of view of the clinician observing signs and symptoms of a patient under care and management.

It is a practical guide to diagnosis and decision making in clinical practice and provides a rich source of information on diseases of the gastrointestinal tract and liver. Covering the full range of examinations in gastroenterology and hepatology, with extremely timely chapters on patients with dyspepsia, eating disorders, jaundice, hepatitis, cirrhosis, and on screening,Principles of Clinical Gastroenterology gives you easy access to approaches that a clinician might take to common symptoms and signs presented by patients with such disorders. The chapters include the epidemiology, history, signs and symptoms, diagnosis, treatment, and prognosis of the most commonly encountered disorders in gastroenterology and hepatology.

This textbook will be an invaluable resource whether you are a gastroenterologist, internist, surgeon, or other clinician who sees patients with gastrointestinal and liver disorders. It should be kept close at hand for frequent consultation.

David H. Alpers, MD, William B. Kountz Professor of Medicine, Department of Internal Medicine, Division of Gastroenterology, Washington University School of Medicine, St. Louis, Missouri, USA

Anthony N. Kalloo, MD, Associate Professor of Medicine, Johns Hopkins University School of Medicine; Director, Division of Gastroenterology and Hepatology, Johns Hopkins Hospital, Baltimore, Maryland, USA

Neil Kaplowitz, MD, Thomas H. Brem Chair, Professor of Medicine, Chief, Division of Gastrointestinal and Liver Diseases; Director, University of Southern California Liver Disease Research Center, Los Angeles, California, USA

Chung Owyang, MD, Professor of Internal Medicine, H. Marvin Pollard Collegiate Professor and Chief, Division of Gastroenterology, University of Michigan Health System, Ann Arbor, Michigan, USA

Don W. Powell, MD, Professor, Internal Medicine, Professor, Neuroscience and Cell Biology; Director, Division of Gastroenterology and Hepatology Program Director, General Clinical Research Center, The University of Texas Medical Branch, Galveston, Texas, USA

Preface.

1 Clinical decision making: Philip S. Schoenfeld (University of Michigan).

2 Economic analysis in the diagnosis and treatment of gastrointestinal diseases: John M. Inadomi (University of California).

3 Psychosocial factors in the care of patients with functional gastrointestinal disorders: Bruce D. Naliboff (University of California), Jeffrey M. Lackner (The State University of New York), Emeran A. Mayer (University of California).

4 Approach to the patient with dyspepsia and related functional gastrointestinal complaints: Nicholas J. Talley (Mayo Clinic Jacksonville), Gerald Holtmann (University of Adelaide, Australia).

5 Approach to the patient with dysphagia, odynophagia, or noncardiac chest pain: Chandra Prakash Gyawali (Washington University School of Medicine), Ray E. Clouse (Washington University School of Medicine).

6 Approach to the patient with gastroesophageal reflux disease: Joel E. Richter (Temple University).

7 Approach to the patient with dyspepsia and peptic ulcer disease: Andrew H. Soll (University of California), David Y. Graham (Baylor College of Medicine).

8 Approach to the patient with gross gastrointestinal bleeding: Grace H. Elta (University of Michigan Health System), Mimi Takami (University of Michigan).

9 Approach to the patient with occult gastrointestinal bleeding: David A. Ahlquist (Mayo Clinic College of Medicine), Graeme P. Young (Flinders University of South Australia).

10 Approach to screening for colorectal cancer: Graeme P. Young (Flinders University of South Australia), James E. Allison (University of California).

11 Approach to the patient with unintentional weight loss: Andrew W. DuPont (The University of Texas Medical Branch).

12 Approach to the patient with obesity: Louis A. Chaptini (University of Medicine and Dentistry of New Jersey), Steven R. Peikin (University of Medicine and Dentistry of New Jersey).

13 Approach to the patient with nausea and vomiting: William L. Hasler (University of Michigan).

14 Approach to the patient with abdominal pain: Pankaj Jay Pasricha (Stanford University).

15 Approach to the patient with gas and bloating: William L. Hasler (University of Michigan Health System).

16 Approach to the patient with acute abdomen: Rebecca M. Minter (University of Michigan Health System), Michael W. Mulholland (University of Michigan).

17 Approach to the patient with ileus and obstruction: Klaus Bielefeldt (University of Pittsburgh), Anthony J. Bauer (University of Pittsburgh).

18 Approach to the patient with diarrhea: Don W. Powell (University of Texas Medical Branch).

19 Approach to the patient with suspected acute infectious diarrhea: John D. Long (Wake Forest University), Ralph A. Giannella (University of Cincinnati).

20 Approach to the patient with constipation: Satish S.C. Rao (University of Iowa).

21 Approach to the patient with abnormal liver chemistries: Richard H. Moseley (University of Michigan).

22 Approach to the patient with jaundice: Raphael B. Merriman (University of California), Marion G. Peters (University of California).

23 Approach to the patient with ascites and its complications: Guadalupe Garcia-Tsao (Yale School of Medicine).

24 Approach to the patient with central nervous system and pulmonary complications of end-stage liver disease: Javier Vaquero (University of Montreal), Andres T. Blei (Northwestern University, Chicago), Roger F. Butterworth (University of Montreal).

25 Approach to the patient with acute liver failure: Ryan M. Taylor (University of Michigan), Robert J. Fontana (University of Michigan).

26 Approach to the patient with chronic viral hepatitis B or C: Sammy Saab (University of California), Hugo Rosen (University of Colorado).

27 Approach to the patient with a liver mass: John A. Donovan (University of Southern California), Edward G. Grant (University of Southern California).

28 Approach to gastrointestinal and liver diseases in pregnancy: Willemijntje A. Hoogerwerf (University of Michigan).

29 General nutritional principles: David H. Alpers (Washington University School of Medicine), Beth Taylor (Barnes-Jewish Hospital, Missouri), Samuel Klein (Washington University School of Medicine).

30 Approach to the patient requiring nutritional supplementation: David H. Alpers (Washington University School of Medicine), Beth Taylor (Barnes-Jewish Hospital, Missouri), Samuel Klein (Washington University School of Medicine).

31 Genetic counseling for gastrointestinal patients: Cindy Solomon (Myriad Genetic Laboratories, Utah), Deborah W. Neklason (University of Utah), Angela Schwab (Intermountain Healthcare, Utah), Randall W. Burt (University of Utah).

Index